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Amid management shakeup, Akcea strikes latest antisense deal

Akcea will bank $250 million up front from a new licensing deal with Pfizer, adding to a balance sheet already fattened by a February deal with Novartis for another antisense oligonucleotide program based on Akcea's technology platform.

The deal gives Pfizer Inc. (NYSE:PFE) exclusive, worldwide rights to AKCEA-ANGPTL3-LRx, which is in Phase II testing to treat Type II diabetes, hypertriglyceridemia and non-alcoholic fatty liver disease (NAFLD). Pfizer

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