NICE rebuffs Gilead’s Yescarta, second setback for an orphan therapy this month

One day after the European Commission approved CAR T therapy Yescarta axicabtagene ciloleucel from the Kite Pharma Inc. unit of Gilead Sciences Inc. (NASDAQ:GILD), U.K.'s NICE published draft guidance recommending against the use of therapy. The guidance applies to adults with relapsed or refractory diffuse large B cell lymphoma (DLBCL) who have received two or more lines of

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