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Sage optimistic about antidepressant’s prospects despite value-destroying Phase III miss

Sage Therapeutics believes a non-compliance issue in one treatment arm may have contributed to its antidepressant’s failure in a key Phase III trial, and company management made a case that the study’s results could still support the candidate’s approval to treat major depressive disorder, along with additional readouts due next year.

Sage Therapeutics Inc. (NASDAQ:SAGE) shed $4.6 billion in market cap,

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