More SMA data at AAN suggest new therapies could displace Spinraza
Novartis continued to add on new data for its spinal muscular atrophy gene therapy Zolgensma at AAN while Roche and Genentech presented updated SMA data for their oral small molecule risdiplam. The dosing and potential efficacy advantages for these agents could overtake Biogen and Ionis' Spinraza, which is currently the only treatment option in this orphan indication.
At the American Academy of Neurology meeting in Philadelphia, Roche (SIX:ROG; OTCQX:RHHBY) and its Genentech Inc. unit presented updated data from part 1 of the Phase II/III FIREFISH trial of risdiplam. Among 17 SMA type