Fecal transplant could treat toxicity common to checkpoint inhibitors

University of Texas MD Anderson Cancer Center researchers used fecal transplants to treat refractory immune checkpoint inhibitor-associated colitis in cancer patients.

Colitis is one of the most common toxicities associated with checkpoint inhibitor immunotherapy, occurring in about 40% of patients. The condition is treated with standard of care (SOC) immunosuppressives, including corticosteroids and tumor necrosis factor α (TNFα) therapies...