11:52 AM
 | 
Jun 19, 2018
 |  BC Extra  |  Clinical News

Sarepta hits high on Phase I/IIa DMD readout

Sarepta Therapeutics Inc. (NASDAQ:SRPT) hit an all-time high Tuesday morning, adding $71.26 (68%) to $176.50 and pushing the company's market cap over $11 billion, after reporting preliminary data from a Phase I/IIa trial evaluating AAVrh74.MHCK7.micro-Dystrophin to treat Duchenne muscular dystrophy. The stock settled during afternoon trading and ended the day up $38.69 (37%) to $143.93.

In three DMD patients in the open-label, U.S. trial, the microdystrophin gene therapy led to mean sarcolemma-localized transduced microdystrophin expression, as measured by the percentage...

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