2:23 PM
 | 
Jun 11, 2018
 |  BC Extra  |  Clinical News

Allergan's atogepant meets in Phase IIb/III to prevent migraine

Allergan plc (NYSE:AGN) said all doses of oral atogepant (MK-8031) met the primary endpoint in the Phase IIb/III CGP-MD-01 trial to prevent episodic migraine. The company declined to disclose next steps for the small molecule calcitonin gene-related peptide (CGRP) receptor antagonist.

On the 834-patient trial's primary endpoint, atogepant significantly reduced mean monthly migraine or probable migraine headache days from baseline over 12 weeks by 4 at the once-daily 10 mg dose (p=0.0236), 3.8 at the once-daily 30 mg dose (p=0.039), 3.6 at the once-daily 60...

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