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6:27 PM
Feb 11, 2016
 |  BC Extra  |  Clinical News

Incyte discontinues Jakafi trials in solid tumors

Incyte Corp. (NASDAQ:INCY) reported 4Q15 and 2015 revenues that beat expectations but fell $6.80 to $65.51 on Thursday after it said it would discontinue all ongoing trials of myelofibrosis drug Jakafi ruxolitinib in solid tumors, including the Phase III JANUS 1 and JANUS 2 trials of Jakafi plus Xeloda capecitabine as a second-line therapy for advanced or metastatic pancreatic cancer.

The biotech said a planned interim analysis of JANUS 1 "did not show a sufficient level of efficacy to warrant continuation," following a...

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