Dynavax preclinical data

In mice, M2e/NP-ISS plus Fluvirin provided 6.9- and 3.4-fold increases in virus neutralization titers against the A/Brisbane/59/2007 H1N1 virus subtype after the 1st and 2nd injection, respectively, compared with Fluvirin alone. A single dose of M2e/NP-ISS plus Fluvirin also provided a 2.6-fold increase in hemagglutination inhibition (HAI) titers against the A/Brisbane/10/2007 H3N2 and B/Florida/4/2006-like strains compared to Fluvirin alone. Data were presented at the Conference on Vaccine Research in Baltimore. ...