BioCentury
ARTICLE | Company News

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August 4, 1997 7:00 AM UTC

PRCT received a $100,000 Phase I SBIR grant from the National Institute of Allergy and Infectious Diseases to support development of a TB vaccine based on the CD1 system. Like the major histocompatibility complex (MHC), a peptide-based system, the CD1 system involves cells that present CD1 molecules as a display for foreign antigens culled from infecting agents. The display stimulates T cells to start an immune offensive against the invaders. Lipid and glycolipid antigens are the players in this system, as compared to peptides in the MHC system. ...