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Targets & Mechanisms

Triplet brings a new strategy to Huntington’s disease

Unveils preclinical POC data for its first DNA damage repair target

Triplet unveils preclinical proof-of-concept data in Huntington’s disease for the company’s first DNA damage repair target.

Apr 27, 2021 | 11:30 PM GMT

Preclinical data suggest that with a new target and route of administration, Triplet’s antisense oligonucleotide for Huntington’s disease may be effective where others have fallen short. 

The Cambridge, Mass.-based company unveiled preclinical data for its first target — DNA damage repair gene MSH3 — at

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