BioCentury
ARTICLE | Product Development

Bispecific constructs move beyond T cell engagers at AACR

Next-generation immune cell engagers and bispecific checkpoints gain ground on T cell engagers at AACR21

April 10, 2021 3:01 AM UTC

T cell engagers have dominated the bispecific antibody scene for the past five years, but the industry is starting to branch out into next-generation structures that offer new functions and potential improvements over first-generation compounds. 

BioCentury’s analysis of the abstracts released ahead of the 2021 American Association for Cancer Research (AACR) virtual conference held April 10-15 finds that T cell engagers account for about half of the abstracts involving bispecific antibodies. ...