What works, what doesn’t and what’s next for COVID-19: Data Byte

The rise of viral variants underscores the continued need to find new treatments for COVID-19, but so far, most therapeutic candidates have performed far worse in late-stage trials than vaccines.

All the vaccine candidates that have made it through Phase III testing have proven effective, particularly at preventing severe disease. Most therapeutic candidates, by contrast, have failed to benefit patients, and some that have met their endpoints offer modest benefit...