Picking vaccine strategies that could hold up to COVID variants

As new mutations to SARS-CoV-2 emerge faster than many countries can vaccinate their populations,  pressure is mounting on vaccine developers to pre-empt the variants before they take hold, let alone are properly characterized.

And while the first wave of vaccines set a new standard for innovation, efficacy and speed, they may be the most vulnerable to escape variants because they all target a single antigen: the spike protein. ...