Distillery Therapeutics


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<h1 class="text title" doc-editable="text" data-component-id="doc-1ef7l992d0">PCF11 binding site on E3 ubiquitin ligase MAGEA11 identified as neuroblastoma target</h1><div class="byline ng-tns-c17-4 ng-star-inserted" data-component-id="doc-1ef7l9he70">
    <span class="ng-tns-c17-4" doc-editable="text">By Claire Quang, Staff Writer</span>
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

St. Jude Children's Research Hospital

DISEASE CATEGORY: CancerINDICATION: Neuroendocrine tumors......

Cancer

Neuroendocrine tumors

PCF11 binding site on E3 ubiquitin ligase MAGEA11 identified as neuroblastoma target

DISEASE CATEGORY: Cancer<br/>INDICATION: Neuroendocrine tumors Interrupting the interaction between the oncogenic E3 ubiquitin ligase MAGEA11 and its substrate PCF11 could treat neuroendocrine tumors.