BioCentury
ARTICLE | Product Development

International group of researchers call Russian COVID-19 vaccine data into question

September 9, 2020 1:28 AM UTC

As researchers cast doubt on the Phase I/II data backing Russian COVID-19 vaccine Sputnik V, the degree to which preexisting antivector immunity dampens vaccine-induced immune responses remains an open question.

Sputnik V comprises an adenovirus serotype 5 (Ad5) vector and an adenovirus serotype 26 (Ad26) vector, each encoding the full-length SARS-CoV-2 spike and each delivered once in separate immunizations...