Russian COVID-19 vaccine induces T cell responses, antibodies on par with convalescent plasma

Clinical readouts for Russian COVID-19 vaccine Sputnik V indicate preexisting immunity against adenoviral vectors don’t necessarily prevent vaccine-induced immune responses against SARS-CoV-2.

Sputnik V comprises an adenovirus serotype 5 (Ad5) vector and an adenovirus serotype 26 (Ad26) vector, each encoding the full-length SARS-CoV-2 spike and each delivered once in separate immunizations...