Amur Pharmaceuticals other research news
Amur researchers have postulated a link between reduced levels of growth hormone and the development of Type II diabetes. As presented at the joint meeting of the European Society for Pediatric Endocrinology and the Lawson Wilkins Pediatric Endocrine Society in Stockholm, the theory suggests that early disruption of the balance between the isoforms of growth hormone leads to increased levels of IGF-2, which competes with insulin at the common receptor, leading to insulin resistance.
Evidence for the theory includes the finding that infants who fail to grow normally in the first year of life tend to develop Type II diabetes as adults. Also, children with deficient growth hormone tend to be extremely sensitive to insulin, while patients with acromegaly (abnormal enlargement of the extremities) have insulin resistance. ...