ARTICLE | Clinical News
Immunex preclinical data
April 15, 2013 7:00 AM UTC
IMNX published in Nature Medicine the ability of Flt-3 ligand to block cancer in an animal model. The agent did not abolish established cancers after a certain time period had elapsed, but did slow tumor growth.
Treatment with daily injections of Flt-3 for 19 days gave complete tumor regression in 38 percent of mice with fibrosarcoma (19 of 50 compared to 1 of 30 control mice, p=0.0001). Five weeks after tumor implant, mean tumor size in treated mice was less than one-third that of controls. ...