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CAR Ts against senescent cells; plus NIH program for ALS, sex-dependent COVID-19 immune responses and more

CAR T liver fibrosis therapy
Memorial Sloan Kettering Cancer Center researchers have generated CAR T cells against PLAUR, which is involved in extracellular matrix remodelling, that could eliminate pathologic senescent cells. Senescent cells have been associated with chronic inflammation that contributes to diseases including liver fibrosis, atherosclerosis and osteoarthritis. The MSKCC team

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