BioCentury
ARTICLE | Product Development

Moderna vaccine first to produce sterilizing immunity in model system -- though only in mice

June 13, 2020 2:10 AM UTC

The first detailed data from Moderna’s COVID-19 vaccine show mRNA-1273 induces neutralizing antibody titers in range of those from other leading candidates, at least in mice, and hint at sterilizing immunity.

Despite the major caveat of the model system, and the difficulty of understanding how the dosing relates to Moderna’s clinical trials, the data provide the first suggestion that a COVID-19 vaccine could be potent enough to shut down SARS-CoV-2 replication. ...

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Moderna Inc.