BioCentury
ARTICLE | Product Development

With time at a premium, Alnylam’s siRNA strategy against COVID-19 could give it an advantage

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May 6, 2020 1:32 AM UTC
Updated on May 6, 2020 at 1:57 AM UTC

Alnylam’s siRNA approach to treating COVID-19 will test the idea that the technology can compete with, and potentially upstage, small molecules and antibodies when it comes to development timelines.

At a minimum, the “front end” of the process, from concept to lead selection, is faster than traditional modalities, John Maraganore, CEO of Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY), told BioCentury. “We went to a candidate in three months -- you can’t do that with a small molecule.” ...