BioCentury
ARTICLE | Product Development

Actemra anti-IL-6 data in COVID-19 outshines Regeneron’s Kevzara readout

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April 28, 2020 1:07 AM UTC

Regeneron shed $2.1 billion in market cap Monday after an IDMC recommended amendments that would narrow the scope of its Phase III trial of Kevzara sarilumab in advanced COVID-19 patients. Also likely weighing on the company’s stock, an investigator-led Phase II trial yielded positive top-line data for Actemra tocilizumab, another IL-6 inhibitor being tested for COVID-19.

But Regeneron did unveil positive late-stage lung cancer data for PD-1 inhibitor Libtayo cemiplimab-rwlc...