BioCentury
ARTICLE | Product Development

Early signs CAR NKs could compete with CAR Ts in heme cancers

CAR NK cells could give CAR Ts a run for their money if early efficacy signals hold up

February 6, 2020 1:04 AM UTC
Updated on Feb 8, 2020 at 3:59 AM UTC

Early clinical data from CAR NK cells have started to roll in, and hint the modality could compete with CAR T cells on efficacy. Built into CAR NK cells are the benefits of off-the-shelf manufacturing and fewer safety risks.

Though the data come from only 11 patients, a study from University of Texas MD Anderson Cancer Center has found an efficacy signal for a CD19-targeted CAR NK cell therapy that is in line with marketed CAR T cells against the same target...