ARTICLE | Targets & Mechanisms
Controlling T cells via epigenetics
INSERM team proposes new autoimmune, immunodeficiency T cell targets in epigenetic pathway
December 20, 2019 2:57 AM UTC
Updated on Dec 20, 2019 at 1:54 PM UTC
An international academic team has discovered an epigenetic pathway that regulates CD4+ T cell differentiation and activity, and could yield new therapeutic targets for autoimmunity.
As drug developers seek the next generation of targeted therapies for autoimmune disease, one hope is that a better understanding of the genetic and molecular determinants of immune cell identity will lead to new therapeutic approaches (see “Rethinking Definitions Of Autoimmune Disease”)...
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Institut National de la Sante et de la Recherche Medicale (INSERM)