BioCentury
ARTICLE | Tools & Techniques

Editing bacterial resistance via gene drives

UCSD study shows how gene drives could tackle antimicrobial resistance

December 20, 2019 12:33 AM UTC
Updated on Dec 20, 2019 at 12:47 AM UTC

In a new take on combating antimicrobial resistance, a UCSD team developed a gene drive system that could reduce resistance more efficiently than conventional CRISPR-based editing.

CRISPR-based gene drive technologies have been used in diploid organisms to copy genes from one chromosome to another via homologous recombination and increase population-wide frequencies of a desired trait. ...