Chipping away at unreliable animal data

Emulate showed its Liver-Chip can both predict clinical safety issues not seen in animal models and identify mechanisms of toxicity, highlighting its benefits for guiding drug development.

Emulate Inc. President and CSO Geraldine Hamilton told BioCentury liver toxicity is a major driver of clinical and marketed drug failures. She said causes include the failure of prior cell-based models to fully recreate liver physiology and the frequently poor correlation between human and animal safety...