GCCR inhibition could treat Ewing sarcoma
October 31, 2019 8:27 PM UTC
INDICATION: Bone cancer
A team from the Weizmann Institute showed that GCCR inhibitors could be repurposed to treat Ewing sarcoma. The GCCR inhibitor Mifegyne mifepristone decreased proliferation in cultures of human Ewing sarcoma cell lines. Mifegyne also reduced tumor growth in three mouse models of the disease, and decreased the number of lung nodules in mice with metastatic Ewing sarcoma...
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