Oct. 3 Preclinical Quick Takes: Funding for NIH hubs; plus a fibroblast inflammasome-metastasis link, iOmx and OSE
NIH funding five translational hubs with $20M
NIH has awarded a total of $20 million across five additional research evaluation and commercialization hubs (REACH). Each hub will identify and financially support biomedical projects that could be translated into diagnostics, devices, therapeutics or tools to improve patient care. The recipients are the Kentucky Network for Innovation & Commercialization; Rutgers Optimizes Innovation Program; Midwest Biomedical Accelerator Consortium; Colorado Anschutz Medical Campus; and the Washington Entrepreneurial Research Evaluation and Commercialization Hub.
Inflammasome activation in fibroblasts linked to breast cancer metastasis
A study in Nature Communications by an Israeli team found that NLRP3 inflammasome activation in cancer-associated fibroblasts (CAFs) promotes breast cancer metastasis by creating an immunosuppressive tumor microenvironment via myeloid-derived suppressor cell recruitment. ...