BioCentury
ARTICLE | Translation in Brief

Cytomegalovirus vectors for a prophylactic HIV vaccine

An engineered cytomegalovirus vector could provide the backbone for a prophylactic HIV vaccine

August 29, 2019 7:39 PM UTC

A spread-deficient cytomegalovirus carrying SIV antigens evoked long-term protective immunity against successive SIV infections in monkeys, suggesting that a prophylactic HIV vaccine can be developed in humans using a similar strategy.

While academics and companies are focusing on harnessing the immune system to eliminate the HIV virus postinfection, they are also looking at ways to prevent HIV infection...