BioCentury
ARTICLE | Emerging Company Profile

Kymera: a systematic approach to protein degradation

Kymera goes beyond empirical approach to protein degradation with Pegasus platform

July 3, 2019 3:53 PM UTC

With a computational drug discovery platform and a proprietary library of E3 ligases and binders, Kymera believes it can accelerate the discovery and development of protein degraders.

Protein degradation is entering the mainstream as a new modality that can direct medicines at proteins often seen as "undruggable,” such as transcription factors, scaffolds in protein complexes and signaling adaptor molecules...