ARTICLE | Preclinical News
Repurposing an HIV target could aid brain injury recovery
February 21, 2019 9:58 PM UTC
Extending CCR5 inhibition beyond treating HIV/AIDS, UCLA researchers showed that blocking CCR5 could promote recovery from stroke and traumatic brain injury (TBI).
CC chemokine receptor 5 (CCR5; CD195) is well known for its role in enabling HIV entry into immune cells, but studies have also shown that blocking the receptor can enhance learning, memory and neuronal plasticity -- processes mediated by mechanisms also involved in brain injury recovery...
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