Palleon: Sweeter checkpoints

How Palleon aims to treat cancer by targeting glycan receptors, ligands

With two platforms targeting glycan ligands and their receptors, and a third to match cancer patients to a therapy, Palleon Pharmaceuticals Inc. aims to treat cancer by removing the brakes on a class of checkpoints found on both adaptive and innate immune cells.

Glyco-immune checkpoints are receptors on immune cells that turn cell activation off when they detect the presence of glycan patterns on tumors. Because glyco-immune receptors occur on both innate and adaptive immune

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