Neurofilament light chain could predict familial Alzheimer's progression

Researchers showed that measuring neurofilament light (NEFL; NF-L) chain could predict progression in familial Alzheimer's disease, suggesting the protein could be used as a biomarker and for developing diagnostics for the disease.

In a paper published in Nature Medicine, scientists from the German Center for Neurodegenerative Diseases (DZNE) and Hertie Institute for Clinical Brain Research used a single molecule array immunoassay to measure NEFL in the CSF and serum of patients from the Dominantly Inherited Alzheimer Network...