BioCentury
ARTICLE | Emerging Company Profile

Sepset’s sepsis signature

How Sepset’s gene expression test could speed up diagnosis of sepsis

November 17, 2018 2:00 AM UTC

Sepset Biosciences Inc.’s gene expression test detects an "endotoxin tolerance" signature that can diagnose sepsis as soon as patients appear in an emergency room, earlier than approved assays and thereby providing more time for antibiotics to kick in to prevent a fatal outcome.

Sepsis is an abnormal immune response to infection that frequently causes organ failure and death. Once thought of as simply out of control inflammation, sepsis is now viewed as mix of hyperinflammation and immune suppression. ...