ARTICLE | Distillery Therapeutics
Cancer
August 23, 2018 3:53 PM UTC
Cell culture and mouse studies suggest inhibiting IRE1 or its RNase activity could help treat triple-negative breast cancer (TNBC). In a panel of human breast cancer cell lines, levels of IRE1 RNase a...
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Endoplasmic reticulum to nucleus signaling 1 (IRE1) (ERN1) (IRE1A)