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ARTICLE | Clinical News

Merck KGaA reports response data for tepotinib in c-MET mutant NSCLC

July 13, 2018 7:59 PM UTC

Merck KGaA (Xetra:MRK) said 500 mg once-daily tepotinib (MSC2167119J) led to a partial response rate of 42.9% and a stable disease rate of 21.4% based on independent assessment in the first 28 patients in the Phase II VISION trial to treat advanced non-small cell lung cancer (NSCLC) in patients harboring c-MET exon 14 skipping mutations.

Based on investigator assessment, tepotinib led to a confirmed objective response rate (ORR) of 53.6% and a stable disease rate of 17.9% in the first 28 patients. ...