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Engine is combining a genetic screen with machine learning to discover targets

Engine Biosciences Pte. Ltd. is marrying a CRISPR-Cas9 genetic perturbation screen with machine learning to delineate how combinations of genes contribute to disease phenotypes and thereby identify novel targets for a range of diseases.

The company, which launched in 2014, holds exclusive rights to combinatorial CRISPR screening technology from the lab of Timothy Lu that was described in a 2016 paper in the Proceedings of the

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