BioCentury
ARTICLE | Preclinical News

PIEZO1 confers resistance to malaria

March 23, 2018 10:45 PM UTC

Scientists at The Scripps Research Institute published a paper in Cell suggesting that a gain-of-function mutation in Piezo-type mechanosensitive ion channel component 1 (PIEZO1) could provide resistance against malaria.

Gain-of-function PIEZO1 mutations lead to hereditary xerocytosis, a blood disorder caused by red blood cell dehydration...