BioCentury
ARTICLE | Preclinical News

CDK6 a potential obesity target

March 13, 2018 9:43 PM UTC

A study published in Nature Communications suggests cyclin dependent kinase 6, a known molecular target for cancer, could also be targeted to treat obesity and metabolic diseases.

White adipose tissue (WAT) stores energy in rodents and humans, while brown adipose tissue (BAT) exudes thermal energy. Beige cells, which are brown adipocytes that develop in white adipose tissues in response to cold and other stimuli, are linked to reduced obesity in rodent models and humans...