ARTICLE | Clinical News
GTx reports additional Phase II stress urinary incontinence data for enobosarm
March 9, 2018 6:58 PM UTC
GTx Inc. (NASDAQ:GTXI) reported data from 18 postmenopausal women with stress urinary incontinence in a Phase II proof-of-concept trial of enobosarm (GTx-024). The candidate is a non-steroidal selective androgen receptor modulator (SARM).
On the primary endpoint of the single-arm, open-label trial, once-daily 3 mg oral enobosarm reduced the mean number of stress urinary incontinence episodes per day by 81% to 1 leak per day at week 12 from 5.17 leaks per day at baseline. Additionally, all 18 patients had a reduction in stress urinary incontinence episodes per day of ≥50% from baseline...
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