Musculoskeletal

Mouse studies suggest CCR5 inhibitors could help treat osteoporosis. In a mouse model of osteoporosis, systemic knockout of CCR5 decreased trabecular bone loss in the femur compared with normal expression. Next steps could include testing CCR5 inhibitors in models of osteoporosis.

Pfizer Inc. and GlaxoSmithKline plc market Selzentry maraviroc, a CCR5 antagonist, to treat HIV/AIDS...