BioCentury
ARTICLE | Clinical News

Pharming reports Phase II data for Ruconest in HAE in pediatric patients

November 30, 2017 11:25 PM UTC

In September, Pharming Group N.V. (Euronext:PHARM) reported data from 20 patients ages 2-13 with hereditary angioedema (HAE) in a Phase II trial showing that 50 IU/kg IV Ruconest conestat alfa (rhC1INH) was safe and well tolerated, with no serious adverse events, hypersensitivity reactions or neutralizing antibodies reported. On secondary endpoints, the product had a median time to onset of relief of 60 minutes and a median time to minimal symptoms of 122 minutes.

The open-label, international trial is evaluating safety and immunogenicity as its primary endpoints. Secondary endpoints include time to beginning of relief, minimal symptoms and complete resolution, pharmacokinetics and pharmacodynamics...

BCIQ Company Profiles

Pharming Group N.V.

BCIQ Target Profiles

Complement 1 (C1) esterase