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ARTICLE | Clinical News

Versartis' somavaratan misses in Phase III for pediatric GHD

September 22, 2017 7:54 PM UTC

Versartis Inc. (NASDAQ:VSAR) said somavaratan (VRS-317) missed the primary endpoint of non-inferiority to Genotropin somatropin in the Phase III VELOCITY trial to treat pediatric growth hormone deficiency (GHD).

In the intent-to-treat (ITT) population, twice-monthly subcutaneous somavaratan failed to show non-inferiority to once-daily Genotropin in annual height velocity at 12 months (9.44 vs. 10.7 cm). Non-inferiority was defined as a lower bound of the 2-sided 95% CI for the difference in height velocity between treatment groups of greater than or equal to -2.0 cm/year. In the ITT population, the lower bound of the 2-sided 95% CI was -2.3 cm/year...