Unlocking liver regeneration

How HepaRegeniX's MKK4 inhibitors could regenerate damaged liver tissue

Although many acute and chronic liver diseases eventually cause liver failure, the only approved treatment is liver transplantation. HepaRegeniX GmbH is developing MKK4 inhibitors to unlock the regenerative capacity of endogenous hepatocytes to treat end-stage liver failure and the liver-damaging diseases that lead to it.

MKK4 is part of a stress signaling cascade in cells and has been investigated as a

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