BioCentury
ARTICLE | Distillery Therapeutics

Cancer

March 21, 2017 6:27 PM UTC

Patient sample and mouse studies suggest inhibiting MCP-1 could help treat glioblastoma multiforme (GBM). In patients, high tumor levels of MCP-1 were associated with poor survival. In a mouse model of GBM, knockout of MCP-1 increased survival compared with normal MCP-1 expression. Next steps could include identifying and testing MCP-1 inhibitors in GBM models...