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Factor XI-inhibiting anticoagulants could also ease arterial hypertension

Factor XI inhibitors may not only have safety advantages over more established anticoagulants, but could come with blood pressure-lowering benefits as well. A Science Translational Medicine study from Ionis Pharmaceuticals Inc. (NASDAQ:IONS) and Johannes Gutenberg University Mainz has shown Factor XI-targeting antisense oligos (ASOs) decrease arterial hypertension by shutting down a feedback loop that fuels inflammation at blood vessel walls, creating new value

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