ARTICLE | Distillery Therapeutics
Therapeutics: Guanine nucleotide binding protein (G protein) q polypeptide (GNAQ; G-ALPHA-q); calcineurin; transient receptor potential cation channel subfamily
May 21, 2015 7:00 AM UTC
Mouse studies suggest inhibiting GNAQ, calcineurin or TRPC6 could help treat focal segmental glomerulosclerosis (FSGS). In kidney podocytes, signaling between GNAQ and calcineurin activates TRPC6. In ...