BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: V-set and immunoglobulin domain containing 4 (VSIG4); CD59; complement C5b-9 membrane attack complex (MAC)

December 10, 2015 8:00 AM UTC

In vitro and mouse studies suggest a VSIG4-CD59 fusion protein could help treat traumatic brain injury (TBI). In vitro, dimers of the VSIG4-CD59 fusion protein bound complement 3b (C3b) with a Kd of 0...