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ARTICLE | Company News

Boehringer licenses CureVac's CV9202

September 19, 2014 2:44 AM UTC

Boehringer Ingelheim GmbH (Ingelheim, Germany) licensed exclusive, worldwide rights to develop and commercialize CV9202 from CureVac GmbH (Tuebingen, Germany). The candidate is in a Phase Ib trial to treat metastatic non-small cell lung cancer (NSCLC). The deal includes a EUR 35 million ($45.3 million) payment to CureVac, which is eligible for up to EUR 430 million ($556.4 million) in milestones, plus royalties.

CV9202 is an mRNA-based vaccine that was developed with CureVac's RNAactive technology. The vaccine codes for six antigens frequently expressed on NSCLC cells: melanoma-associated antigen family C 1 (MAGEC1), MAGEC2, cancer/testis antigen 1B ( CTAG1B; NY-ESO-1), survivin (BIRC5), oncofetal antigen 5T4 and mucin 1 ( MUC1; CD227). ...